Photodynamic Therapy (PDT)
Targeted Field Treatment for Sun Damage and Precancerous Skin Changes
Photodynamic therapy (PDT) is one of the most effective medical treatments available for widespread sun damage, particularly when precancerous changes like actinic keratoses are present. At Northern Sydney Dermatology & Laser, we use a laser-assisted PDT protocol (L-PDT), guided by Dr Nina Wines, a laser and procedural dermatologist with extensive experience in treating sun-damaged skin.
What Is Photodynamic Therapy?
PDT is a dermatologist-performed procedure that uses a light-sensitive agent (photosensitiser) activated by a specific wavelength of light to selectively destroy damaged or precancerous skin cells. When combined with laser pre-treatment, the effect is enhanced—both for visible results and for medical benefit.
How We Perform PDT at Our Clinic
Our Laser-Assisted PDT (L-PDT) protocol includes:
Step 1: Laser Activation
We use fractional lasers to gently prepare the skin, allowing deeper and more uniform absorption of the photoactive agent.Step 2: Application of the Photosensitiser
A special agent (usually ALA) is applied to the skin and allowed to incubate, soaking into abnormal cells.Step 3: Light Activation
A specific blue or red light activates the agent, selectively destroying damaged skin cells while sparing healthy tissue.
This combination enhances both the effectiveness and the aesthetic benefit of traditional PDTUnderstanding 'Field Damage'
FAQ: Photodynamic Therapy
Q: How long is recovery after PDT?
Most patients experience redness, mild swelling, and peeling for about 5–7 days. We provide full aftercare guidance to support your recovery.
Q: Is PDT painful?
Mild discomfort can occur during light activation, described as tingling or warmth. We offer cooling and preparation strategies to make the process more comfortable.
Q: How many sessions are needed?
One session may be sufficient for mild to moderate sun damage. For advanced field damage, a series of treatments may be recommended.
Q: Can PDT prevent skin cancer?
Yes. When performed correctly, PDT targets abnormal, precancerous cells and has been shown to reduce the risk of keratinocytic skin cancers.
Q: Is it safe for everyone?
PDT is suitable for many skin types, but not all. We’ll advise you during consultation if L-PDT or another method is better for your skin and goals.
Results vary between individuals. Images are of patients treated by Dr Nina Wines and are published with their consent. These are for illustrative purposes and are not a guarantee of results
Scientific Evidence: PDT & Laser in Skin Cancer Prevention
Recent studies support the preventive power of laser and PDT:
Benson et al. found a 50% reduction in new facial skin cancers after fractional laser treatment.
Brewer et al. demonstrated that the 1927nm fractional laser, when used regularly, also reduced new keratinocytic skin cancers over time.
These findings suggest that when performed by skilled dermatologists, PDT and fractional lasers are not just cosmetic—they’re protective.
Progress following L-PDT.
Patients experience during and following L-PDT
Before and After L-PDT
Multi-stacking of Lasers
After L-PDT patients can then undergo stacked lasers to address all other elements of photo damage, resurface the skin and improve the overall outcome.
Click here to watch a webinar on laser assisted drug delivery for sun damage.
All medical and laser procedures carry some risks. The information provided here is general in nature and not a substitute for a professional medical consultation. For advice tailored to your skin and health, please book an appointment with Dr Nina Wines.